Liquid biopsy group is focused on studying the tumour material in biological fluids, mainly blood from breast and prostate cancer patients. There are different tumour materials that can be analysed: circulating tumour cells (CTCs) which cause metastasis, tumoural genetic material ctDNA/ctRNA, extracellular vesicles and other blood components such as platelets.
Our main goal is isolated and molecular characterized both CTCs and tumoral genetic material in the circulatory system to identify prognostic biomarkers of response, resistance and possible therapeutic targets.
Ongoing projects:
- Liquid biopsy for precision oncology.
- Identification of resistance mechanisms to systemic treatment in Luminal advanced breast cancer.
- New approaches in Liquid Biopsy: study of blood biomarkers with diagnostic utility in breast cancer and its function in the metastatic cascade.